You are here:

Urology/sparfloxacin, gatifloxain, or minocycline for prostatitis


More than 20 years in treating prostatitis wrote at 2011-10-16 05:34:50
No, Minocycline is better than the Doxycycl in treating the CHRONIC or RECURRENT prostatitis because the Minocycline can penetrate tissues better.

GRB wrote at 2012-05-03 01:09:16
cephalosporin including IV have poor penetration into the prostate, a visit to ID doc is good idea; sometimes IV abx are  needed.

swleslie wrote at 2012-05-29 23:45:17
Yes, minocycline does penetrate better but it has more side effects and is tougher on the stomach so we usually use the doxycycline.  

It's also true that cephalosporins don't penetrate the prostate well, but they have good coverage for gram positives and occasionally this will help when other meds have failed.

LeeS773 wrote at 2013-02-02 02:34:44
Minocycline has the best penetration into brain and prostate so I would have treated you with that from the start. It's also not very expensive and has a low incidence of side effects.

You should also ... um.... empty.... it often but do it manually or with protection as it could infect a partner.  


All Answers

Answers by Expert:

Ask Experts


Stephen W. Leslie, MD


Questions concerning erectile dysfunction, kidney stones and prostate disorders including prostate cancer. I have a special interest in kidney stone disease prevention.


Full time practicing urologist with 30 years experience. Associate Professor of Surgery and Chief of Urology at Creighton University Medical Center. Editor in Chief of eMedicine Urology internet textbook. Author of only NIH approved book written for patients by a urologist on the subject of kidney stones "The Kidney Stones Handbook". Inventor of the "Parachute" and "Escape" kidney stone baskets and the "Calculus" stone prevention analysis computer program.

American Urological Association, Ohio State Medical Association, Sexual Medicine Society

Men's Health, Journal of Urology, Urology, Healthwatch Magazine, Emergency Medicine Monthly, eMedicine, "The Kidney Stones Handbook", and numerous articles in various newspapers. He is also the editor of the Urology Board Review by McGraw-Hill used by urologists to study for their Board Certification Examinations.

Graduate of New York Medical College with residencies completed at Metropolitan Hospital New York, Albany Medical Center and University of Wisconsin-Madison.

Awards and Honors
Thirlby Award of the American Urological Association. Rated as one the country's Best Urologists by the Independent Consumer's Research Institute

©2017 All rights reserved.