AllExperts > Urology 
Search      
Urology
Volunteer
Answers to thousands of questions
 Home · More Urology Questions · Answer Library  · Encyclopedia ·
More Urology Answers
Question Library

Ask a question about Urology
Volunteer
Experts of the Month
Expert Login

Awards

About Us
Tell friends
Link to Us
Disclaimer

 
 
 
 
About Arthur Goldstein, M.D.
Expertise
Any problems or questions related to the field of urology; ie urinary stone disease, urinary cancers (kidney, bladder, prostate, testis, etc.), urinary infections, impotency, etc.

Experience
I am retired from the active practice of urology. My 34 years was totally in the clinical field and involved the entire gamut of genitourinary problems, with special interest in male impotence and endourology.

Organizations
American Medical Association, American Urological Association, American College of Surgeons

 
   

You are here:  Experts > Health/Fitness > Urology > Urology > calcifications in testis

Urology - calcifications in testis


Expert: Arthur Goldstein, M.D. - 2/21/2007

Question

-------------------------------------------
The text above is a follow-up to ...

-----Question-----


sir for what purpose the tablet androz-50 is given.

its a siledenfil citrate.
sir,
i'm having calcifications in testis with left varicocele.i'm fearing that calcifications will turn in to tumor.will that tumor will change in to malignancy.i have took a scan b4 10 months.ath that time i have no problem.with what interval i have to take scan.with in 6 months r in a year.if that calcifications turn in to tumor what will the surgeons do.will i die due to this calcifications.kindly tell me the details abt this sir.i had a fear abt that left varicocele.

thank u sir
-----Answer-----
S. M. calcifications in the testicle and varicocele are 2 differnet conditions that really having nothing to do with each other.

A varicocele is a collection of varicose veins of the spermatic cord (the rope-like structure that suspends each testicle).  They occur in about 15% of the population.  More than 90% occur on the left, 5% on the right and the rest are bilateral.  Varicoceles are due to a defective valve in the vein that drains blood from the testicle.  They fill by gravity and therefore are not detectable while recumbent but apparent when upright.  On examination, the lesion feels like a bag of worms.  Small varicoceles may only be detected by imaging studies such as ultrasound.  A varicocele that does not disappear when lying down may indicate a tumor in the abdomen (but this is quite unusual).  Varicoceles are generally painless.  Often men present to the doctor with pain in the testicle and the varicocele is discovered at that time.  In my experience, the pain is very rarely due to the vairicoele and usually due to prostatitis (an inflammation of the prostate gland).  In other words, the varicocele is an incidental and unrelated condition.  Varcioceles may cause an infertility problem manifest by lower sperm counts and increased numbers of immature sperm in the semen on analysis.  However, the majority of men with varicoceles do  NOT have infertility.  Of men who have abnormal semen analyses and varicoceles,  in about 70% of them, the 2 are related and fixing the varicolele often will improve their fertility.  If a teenager or young man with a varicocele has a smaller than normal testicles on that side, there is an increase risk of infertility and many urologists consider this an indication to fix the varicocele surgically.   

Calcifications in the testicle are most often incidentally detected by imaging studies of the testes, such as by ultrasound.  The most common type of calcification is microlithiasis which is characterized by multiple small (1-2 mm), diffusely scattered calcifications.  In a study by Peterson et al in the Journal of Urology (volume 166, pp 2061-2064, December 2001) the incidence of microlithiasis in 1504 men between the ages of 18 and 35 was 5.6%.  None of these men had positive tumor markers or clinical evidence of testicular cancer.  The incidence of testicular tumor in the male population is only 3-5 men per 100,000 (.003-.005%).  Although tumors of the testicle may exhibit calcification, the majority of calcifications are of a benign nature.  The calcifications in tumors are usually larger, less regular and fewer in number.  The cause of most calcifications is thought to be due to some degeneration of seminiferous tubules (tubules that manufacture sperm), old trauma or inflammation.  Calcifications themselves do not require treatment.  However, because of the possible occasional association with testicular tumor, period re-evaluation by physical examination and ultrasound are suggested.  Good luck.


Answer
S, M,. I was not familiar with the drug Androz-50 so I had to look it up.  It is a generic form of Viagra 50 mgm manufactured by a company called Torrent.  I have never heard of them.   Viagra (as well as Cialis and Levitra) are a class of drugs called PDE 5 inhibitors.  They are used to help impotent men get erections.  PDE5 inhibitors (in proper dosage which varies with the individual) have shown success in about 80 of patients.  Side effects may include headaches, flushing, heart- burn, nasal congestion, visual disturbances, dizziness, etc.  These drugs are contraindicated in patients with coronary artery disease who take nitrates (ie nitroglycerine) as some deaths have occurred in this group.   There is also the potential for severe side effects if PDE5 inhibitors are used in patients who take alpha- blockers (ie Hytrin, Cardura, etc.) or are hypertensive.  Several other types of medication may alter the blood level of PDE5 inhibitors possibly leading to significant side effects.  Other contraindications include certain types of liver and visual disorders (ie retinitis pigmentosa).  PDE5 inhibitors have been noted to cause abnormal liver function tests in some otherwise normal men.  Because of this, although PDE5 inhibitors are well tolerated by most, they should only be taken with caution, under the supervision of a physician and for the proper indication. .  In addition, I would be very wary about taking this drug in generic form as it has not yet been certified for this compounding, at least in the USA and I know nothing about the quality control program of Torrent pharmaceutical company.  

Add to this Answer   Ask a Question


 
User Agreement | Privacy Policy | Kids' Privacy Policy | Help
Copyright  © 2008 About, Inc. AllExperts, AllExperts.com, and About.com are registered trademarks of About, Inc. All rights reserved.